MyBioSource.com's DNAJC24 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The DNAJC24 Antibody (Center) was generated using DNAJC24, and DPH4 as the antigen and it reacts with Human.
Description
Diphthamide is a unique posttranslationally modified
histidine found only in translation elongation factor-2 (EEF2; MIM
130610). This modification is conserved from archaebacteria to
humans and serves as the target for ADP-ribosylation and
inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas
exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of
diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied
by OMIM]